Verification isn’t a feature. It’s the architecture.
Every output includes explicit verification status, evidence hierarchy classification, and full reasoning traces. Nothing is hidden.
core architectural principleHow we ensure
accuracy
Every insight is verified using evidence hierarchy and a final human quality gate.
PICO - Structured verification
Evidence hierarchy labeling
Human quality gate
VERIFICATION ARCHITECTURE
Every statement receives an explicit status
No ambiguity. No hidden interpretations. Each scientific claim is assessed against the evidence and assigned a clear status with detailed rationale.
Drug X demonstrates statistically significant improvement in progression-free survival compared to standard of care.
This claim is unequivocally verified. Three Phase III RCTs (Evidence 12, 23, 45) report consistent PFS benefit with hazard ratios ranging from 0.58–0.67. The 2024 NCCN Guidelines (Evidence 78) cite this as a Category 1 recommendation.
Powered by the Glass Box architecture: The Verification Engine can only assess evidence that has been pre-indexed and audited by upstream agents. It cannot fabricate sources.
See how the architecture works
Claims specific enough
to verify
Before evidence can be matched, the system decomposes every candidate claim into the PICO framework. This ensures we're verifying the specific assertion-not a vague generalization.
A claim of "superior efficacy" is only verified if the specific Population and Comparator match the evidence. No shortcuts.
EVIDENCE HIERARCHY
Instantly assess the
weight of any reference
Every source in the Evidence Library is classified by study type. This allows instant assessment of evidentiary weight—and ensures your reviewers can quickly identify the strength of support for any claim.
Language neutralization
Promotional language identified automatically
The platform automatically detects subjective or promotional language and refines it into scientifically precise, verifiable statements. No more manual scrubbing.
This isn’t just word-swapping. The system evaluates whether the underlying claim can be supported by the evidence—and adjusts the precision accordingly.
BEFORE
Drug X demonstrates robust efficacy with a dramatic improvement in survival outcomes.
AFTER
Drug X demonstrates statistically significant efficacy with a median OS improvement of 4.2 months (HR 0.68, p=0.01).
Bi - directional mapping
Trace evidence to statement - or the reverse
Every Acceleration Package includes bi-directional traceability. Our system can audit in whichever direction they prefer.
Statement
Click any statement in the document to see exactly which sources support it, with the specific sentences and data points highlighted.
Statement
Click any source in the Evidence Library to see all statements it supports, ensuring no evidence is orphaned or misapplied.
Conflict Identification
When evidence conflicts, we show both sides
General-purpose AI chooses one interpretation and hides the conflict. Posterios flags it explicitly—providing a transparent picture for informed decision-making.
Conflicts are documented in the Reasoning Trace, with explicit notation of which sources diverge and why the final status was assigned.
Evidence conflict detected
Source A (Phase III RCT)
Reports significant PFS benefit (HR 0.58).
Source B (Real-world study)
Reports modest benefit (HR 0.82) in community setting.
Resolution: Statement qualified to specify “in controlled trial settings”.
HUMAN QUALITY GATE
AI generates
Humans validate
Every Acceleration Package passes through a structured scientific validation protocol — a human-in-the-loop step where scientific analysts audit the AI’s work before delivery
Verification audit
Analyst reviews verification statuses and spot-checks rationale against source documents.
Mapping validation
Analyst confirms bi-directional tracing is accurate and no evidence is orphaned.
Final sign-off
Analyst provides scientific sign-off before package is released to client.