Three principles that make the difference
Glass Box
The AI that writes your documents cannot access the open internet. It can only use curated evidence verified by upstream agents.
Not: Black Box generation with high risk of fabrication
Strategic Memory
Strategic context critical for accuracy - imperatives, constraints - persists across projects, always under your control.
Not: session-based AI that forgets critical instructions
Life Sciences Only
Purpose-built for pharma strategy. PICO verification, evidence hierarchies, and language neutralization are native.
Not: General-purpose AI adapted for healthcare
Two ways to accelerate
DOCUMENT ACCELERATION
The scientific foundation that powers your document
We deliver verified scientific synthesis, curated evidence libraries, and full reasoning traces. Your medical writers move directly to crafting the final narrative.
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Every claim traced to verified evidence
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PICO-structured clinical data extraction
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Language neutralization built-in
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Bi-directional source mapping
STAKEHOLDER SIMULATION
Test your strategy before the real world does
Simulate advisory boards and strategic surveys with Al expert personas. Get actionable insights and plausible scenarios in weeks , not months.
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Realistic expert personas from real KOL profiles
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Sentiment and theme analysis automated
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Iterative refinement of messaging
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Structured report with key quotes
Glass Box Architecture
Five specialized agents.
One chain of custody.
Posteros doesn't use a single Al to do everything. We use a linear assembly line of specialized agents, each with a specific job and strict constraints on what they can access.
THE CRITICAL CONSTRAINT
The Writer Agent is forbidden from accessing the internet. It can only synthesize evidence that has already been verified by the upstream agents.
Because the writer agent only works with pre-verified curated evidence, every output is grounded in that evidence — not generated from thin air.
The Architect
"What do we need to prove?"
Analyzes the OSW (Objective, Scope, Watchouts) and breaks down high-level objectives into specific, verifiable hypotheses. Translates business questions into scientific claims that can be tested against evidence.
RECEIVES
OSW Document, Strategic Context
PASSES FORWARD
Candidate Statements, Key Intelligence Questions
The Researcher
"Find everything on this topic."
Executes comprehensive searches across academic databases, clinical trial registries, and regulatory sources. Builds the raw Search Index that contains every potentially relevant source.
RECEIVES
Candidate Statements, Search Parameters
PASSES FORWARD
Raw Search Index (DOIs, PMIDs, NCT IDs)
CONSTRAINT
Can only search sources defined in scope. Cannot modify the hypotheses.
The Auditor
"Does this source prove the claim?"
Reads source documents and evaluates whether they actually support the candidate statements. Applies PICO structuring to ensure precise matching. Assigns verification status.
RECEIVES
Candidate Statements, Raw Search Index
PASSES FORWARD
Statement–Evidence Mappings, Verification Status
CONSTRAINT
Can only read sources in the Index. Cannot search for new sources.
The Curator
"Is this evidence strong enough?"
Applies evidence hierarchy rules to filter and prioritize sources. Ensures the final Evidence Library contains only high-quality, relevant citations.
RECEIVES
Statement–Evidence Mappings, Hierarchy Rules
PASSES FORWARD
Curated Evidence Library
CONSTRAINT
Cannot override Auditor verification status. Can only rank and filter.
The Writer
"Synthesize the verified facts."
Assembles the final narrative from verified evidence. Applies language neutralization. Generates the AI Narrative Report with complete traceability.
RECEIVES
Curated Evidence Library, Document Structure
PASSES FORWARD
AI Narrative Report, Reasoning Trace
CONSTRAINT
Cannot access the internet. Can only use evidence from the Curator's Library.
Strategic Memory
Your context persists.
Your constraints are enforced.
Every engagement starts with the OSW Framework. We capture not just what you want—but what you explicitly don't want. These become hard constraints in the system.
Your Watchouts aren't documented in a briefing document that gets forgotten. They're configured into the Reasoning Engine, Constraining the system from generating prohibited logic.
Life Sciences Only
Verification isn't a feature.
It's the architecture.
Every output includes explicit verification status, evidence hierarchy classification, and full reasoning traces. Nothing is hidden.
Drug X demonstrates statistically significant improvement in progression-free survival compared to standard of care.
Drug X offers a compelling value proposition for early-stage patients based on its efficacy and safety profile.
Drug X demonstrates statistically significant improvement in progression-free survival compared to standard of care.
Drug X offers a compelling value proposition for early-stage patients based on its efficacy and safety profile.
foundational principles
PICO structuring. Every clinical claim decomposed into Population, Intervention, Comparator, Outcome before verification.
Evidence hierarchy. Every source classified: Meta-Analysis, RCT, Guideline, RWE, Case Series, automated weight assessment.
Bi-directional mapping. Click any statement to see its sources. Click any source to see what statements it supports.
Language neutralization. Promotional language automatically identified and refined to verifiable, objective statements.
Enterprise isolation. Your data never trains public models. Isolated database schema per client. Pre-launch confidentiality maintained.
Full audit trail. Every output includes Reasoning Trace Reports. Transparency into how every conclusion was reached.
Human quality gates. Scientific analysts validate every deliverable. Nothing ships without human sign-off.
See the rigor for yourself
We'll walk you through a real Acceleration Package tailored to your therapeutic area. See the verification engine, the evidence traceability, and the audit trail in action.